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Dr Harveen Singh

Paediatric Gastroenterologist and Hepatologist, Sydney

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Inflammatory Bowel Disease

Crohn's Disease vs Ulcerative Colitis in Children

Published 29 September 2025
6 min read
HS

Dr Harveen Singh FRACP

Paediatric Gastroenterologist & Hepatologist | Reviewed 29 September 2025

Inflammatory bowel disease (IBD) is an umbrella term for chronic conditions that cause inflammation in the digestive tract. The two main types — Crohn's disease and ulcerative colitis (UC) — share some features but are distinct conditions with different patterns of inflammation, complications, and treatment approaches.

Key Differences at a Glance

FeatureCrohn's DiseaseUlcerative Colitis
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LocationAny part of the GI tract (mouth to anus)Large intestine (colon and rectum) only
PatternSkip lesions (patchy inflammation)Continuous inflammation
DepthFull thickness of gut wallMucosal (inner lining) only
Common symptomsAbdominal pain, diarrhoea, weight loss, perianal diseaseBloody diarrhoea, urgency, cramping
Extraintestinal featuresMore commonLess common
Curative surgeryNot possiblePossible (colectomy)

Symptoms in Children

Children with IBD often present differently from adults. Common features include:

  • Growth failure or delayed puberty — often the first sign in adolescents
  • Abdominal pain, especially around meals
  • Diarrhoea, with or without blood
  • Fatigue and pallor (from anaemia)
  • Weight loss or failure to gain weight appropriately
  • Perianal disease in Crohn's — skin tags, fissures, or fistulas around the anus
  • IBD should be considered in any child with unexplained growth problems, chronic diarrhoea, or recurrent abdominal pain.

    How Is IBD Diagnosed?

    Diagnosis requires:

  • Blood tests — to look for inflammation (CRP, ESR), anaemia, and nutritional deficiencies
  • Faecal calprotectin — a stool test that is elevated in intestinal inflammation; useful for monitoring as well as initial assessment
  • Colonoscopy and gastroscopy with biopsies — essential to confirm diagnosis, determine the extent and type of IBD, and guide treatment
  • Imaging (MRI or ultrasound) — particularly for Crohn's disease, to assess the small bowel and detect complications
  • Treatment Approaches

    IBD treatment in children aims to achieve and maintain remission, support normal growth, and minimise side effects.

    For both Crohn's and UC:

  • 5-aminosalicylate (5-ASA) medications — more effective in UC
  • Corticosteroids — used for flares but not long-term maintenance
  • Immunomodulators (azathioprine, methotrexate)
  • Biologic therapies (infliximab, adalimumab) — increasingly used in moderate-to-severe disease
  • Exclusive enteral nutrition (EEN) — a liquid diet used as a first-line treatment in Crohn's disease, particularly in children; highly effective
  • Early, effective treatment is key to preventing complications and supporting healthy growth. Dr Harveen Singh FRACP provides specialist paediatric IBD care at clinics across Sydney.

    Last reviewed by Dr Harveen Singh FRACP, Paediatric Gastroenterologist & Hepatologist

    IBDCrohn's diseaseulcerative colitisinflammatory bowel diseasechildren

    Concerned About Your Child?

    Dr Harveen Singh FRACP sees children across Sydney at Bankstown, Westmead, St Leonards, and Campbelltown. A referral from your GP or paediatrician is required.